SOD (Superoxide Dismutase)

by Maxime Vanhulle – May 12, 2025

SOD (Superoxide Dismutase): A Deeper Look at the Ultimate Antioxidant for Skin and Health

In our previous blog we discussed how antioxidants like SOD help neutralize free radicals and thus protect the skin and cells. But why does SOD deserve its own, deeper spotlight?

Let’s take a closer look at how SOD works , what the science behind it is, and why this enzyme is increasingly appearing in skin and health supplements like those from B.me.

What makes SOD unique among antioxidants?

Most antioxidants (such as vitamins C and E) work extracellularly , that is, outside the cells.
SOD, on the other hand, works intracellularly : it is located in the mitochondria and the cytosol, where energy production takes place and where most free radicals are created. This makes SOD the first line of defense against oxidative stress (Islam et al., 2022, PubMed ).

In addition, SOD can specifically target superoxide radicals — a highly reactive type of ROS (reactive oxygen species) that rapidly damages DNA, lipids and proteins.

Scientific evidence and applications

According to an extensive review in PubMed Central (PMC5969776), SOD enzymes have been studied for:
✅ Reduction of oxidative stress in chronic diseases
✅ Support of anti-inflammatory processes in arthritis and inflammatory skin diseases
✅ Protection against UV damage in the skin
✅ Reduction of muscle pain and recovery after intensive training

SOD supplementation is also being investigated for potential applications in neurodegenerative diseases, although further research is needed.

Why is oral intake of SOD not easy?

An important detail: SOD is a protein , which means that it can be broken down in the stomach before it is actively absorbed. That is why you see more and more use in the supplement industry of:

  • SOD complexes with gliadin, which provide protection against breakdown

  • Plant sources with natural SOD activity, such as melon extract (for example the branded raw material Extramel®)

  • Topical (external) applications in skincare

How does SOD work in combination with other ingredients?

At B.me we cleverly combine antioxidants in formulas. For example, SOD, vitamin C, zinc and biotin work complementary to:
✨ reduce oxidative stress
✨ to support collagen synthesis
✨ strengthen the skin barrier

This synergy is essential, because no single ingredient works optimally on its own.

Want to read more about the science behind SOD?

For those who want to dive deeper, check out these references on PubMed:

👉 Curious about how we incorporate SOD into our skin formulas? Discover our offering at bmeskin.com .

by Maxime Vanhulle – May 12, 2025

Leave a comment

Please note, comments need to be approved before they are published.

Related Blogs

chevron_leftchevron_right
Waarom vloeibaar collageen beter is dan poeder

B.me – by Camille Wille

Why Liquid Collagen is Better Than Powder

From the age of 25, the natural production of collagen slows down. This process accelerates due to stress, sunlight, sugar and smoking — which becomes visible in your skin: fine lines, less elasticity and loss of hydration. More and more people are therefore opting for a supplement. But which form is the most effective? In this article you will discover why liquid collagen is preferred over powder or capsules, how to achieve the best results and why our Collagen Advance+ is the ideal daily boost. What is liquid collagen? Liquid Collagen is a ready-to-use formula of hydrolyzed collagen peptides that you take directly. Thanks to its liquid form, it is absorbed faster and more efficiently in your body than collagen powder, which must first be digested. In addition to 10g of collagen, our Collagen Advance+ also contains hyaluronic acid, zinc, silicon and vitamin C — a combination that supports the body in maintaining firm and hydrated skin. 3 Benefits of Liquid Collagen Over Powder 1. Faster absorption and high bioavailability The absorption of liquid supplements is on average 1.5x more efficient than powder. Our ampoules have a bioavailability of no less than 91%. 2. No mixing stress or aftertaste Liquid shots are ready to use and tasty — no lumps or powdery aftertaste. The subtle raspberry flavor of Collagen Advance+ even makes your daily routine something to look forward to. 3. Consistent dosage With a 25ml shot you get exactly what your body needs, without weighing or shaking. Each ampoule contains a scientifically proven dosage of active ingredients. What do users say? Customers who switched from powder to liquid ampoules report that they can more easily integrate the product into their morning routine and experience fewer side effects such as bloating. How do you take it? Take 1 ampoule of our Collagen Advance+ daily — preferably at a fixed time, for example with breakfast. Shake shortly before use and drink it pure or mix it in your smoothie. Tip: For optimal results, take it consistently for at least 8-12 weeks. Conclusion Want to get the most out of your collagen routine? Choose a formula that is easily absorbed, tastes good and focuses on skincare from the inside out. Our Collagen Advance+ combines liquid absorption with powerful ingredients — no added sugars or sweeteners. Discover Collagen Advance+ and give your skin the daily support it deserves.

Read more

Collageen - de basis voor een stevige, stralende huid

B.me – by Camille Wille

Collagen - the basis for firm, radiant skin

Why is collagen so important for your skin? Collagen is a naturally occurring protein in the body. It is not only in your skin, but also in your bones, tendons, cartilage, hair and nails. Collagen is essential for the skin: it contributes to the structure, firmness and suppleness. From about the age of 25, natural collagen production decreases. This can lead to fine lines and less elastic skin over time. Factors such as UV exposure, smoking, sugar intake and stress can accelerate this process. More and more people are therefore looking for ways to provide additional support to their skin from within. How can you support collagen? 1. Collagen through supplements Collagen supplements are more popular than ever. Daily intake of collagen, along with other supporting ingredients such as vitamin C and hyaluronic acid, is increasingly chosen by those who care about their skincare routine. Important to know: The bioavailability and composition of a supplement make a big difference. A formula with highly absorbable collagen peptides and supporting nutrients can help support your skin from the inside out. At B.me we developed Collagen Advance+ for this purpose, a liquid formula that: Contains 10g of hydrolyzed collagen peptides Enriched with vitamin C, silicon, hyaluronic acid and zinc 91% bioavailability has Contains no added sugars or sweeteners Our liquid shots are easy to take, without the hassle of powders or capsules. Discover Collagen Advance+ here 2. Stimulate collagen through skin care Topical products such as creams and serums can help care for the skin barrier. Ingredients such as peptides and antioxidants support the natural processes in the skin. Although collagen molecules themselves are too large to penetrate deep into the skin, smaller molecules can provide signals that help the skin renew itself. 3. Professional treatments Treatments such as microneedling and hyaluronic acid injections can help stimulate natural collagen production. This activates the fibroblasts in the skin, which contributes to a firmer skin structure. Although such treatments can be effective, many people opt for a combined approach: support from within and care from outside. Why choose Collagen Advance+ from B.me? Our Collagen Advance+ shots are specially developed to support your skin from within on a daily basis. Thanks to the high dosage, pure ingredients and liquid form, it is a simple and effective addition to your routine. Choose an approach that truly nourishes your skin, from within. Discover Collagen Advance+ here Please note: food supplements are not a substitute for a varied and balanced diet or a healthy lifestyle. Results may vary from person to person.

Read more